Nucleic Acid Synthesis
Medchemexpress LLC 2′-O-Methyluridine | 2140-76-3 | 99.81% | 258.23 | 1 G
2′-O-Methyluridine is a modified nucleoside found in T. thermophile tRNA. Its serum level is decreased in breast cancer patients. It can be incorporated into siRNA targeting the gene encoding apolipoprotein B, which reduces ApoB protein levels in HepG2 and prevents IFN-α production in isolated human PBMCs.
- Modified nucleoside
- Found in T. thermophile tRNA
- Decreased in serum levels in breast cancer patients
- Used in siRNA targeting apolipoprotein B
- Reduces ApoB protein levels
- Prevents IFN-α production
Cambridge Isotope Laboratories 2'-DEOXYCYTIDINE 5'-MONOPHOSPHATE (15N3, 96%), 10 MG
2'-DEOXYCYTIDINE 5'-MONOPHOSPHATE (15N3, 96%), 10 MG
Medchemexpress LLC 5-fluorocytidine | 2341-22-2 | MFCD00210953 | 97.0% | 261.21 g/mol | C9H12FN3O5 | 1 G
5-fluorocytidine is a fluorinated cytidine nucleoside that inhibits maturation of the 45S ribosomal RNA precursor and is provided as a characterized research reagent with storage and safety guidance from product datasheets and SDS.
- Fluorinated cytidine nucleoside.
- Inhibits maturation of the 45S ribosomal RNA precursor.
- Molecular formula C9H12FN3O5.
- Molecular weight 261.21 g/mol.
- Storage: 4°C under nitrogen; in solvent: -80°C for 6 months, -20°C for 1 month.
Medchemexpress LLC Trifluridine/tipiracil hydrochloride mixture | 733030-01-8 | 100.0% | 435.76 | 50 MG
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a potent and orally active nucleoside antitumor agent. It is composed of a 1:0.5 molar mixture of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). The antitumor activity primarily stems from its inhibition of thymidylate synthase (TS) and its incorporation into DNA.
- Potent and orally active nucleoside antitumor agent
- Composed of a 1:0.5 molar mixture of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI)
- Inhibits thymidylate synthase (TS)
- Incorporates into DNA for antitumor activity
Apexbio Technology LLC EZLink Sulfo-NHS-SS-Biotin Kit, 10 reactions
The EZLink Sulfo-NHS-SS-Biotin Kit contains reagents sufficient for 10 biotin labeling reactions. It is a water-soluble biotin reagent for labeling protein, antibody or other molecules with amidogen (NH2-). The biotin in the kit is sufficient and has been activated for direct use. The whole procedure is simple and quick. Other sizes are available. Please inqury us for quote.
Cayman Chemical Indole-3-thIo CarboxamIde 1g
A synthetic intermediate useful for pharmaceutical synthesis
Cayman Chemical ANTIBODY SGC3027 1mg
A prodrug form of the PRMT7 inhibitor SGC8158; converted by intracellular reductases to SGC8158; inhibits methylation of Hsp70 in vitro (IC50 = 2.4 µM)
Medchemexpress LLC 2'-O-Methyluridine | 2140-76-3 | 99.8% | 258.23 | 5 G
2'-O-Methyluridine is a modified nucleoside that can be found in *T. thermophile* tRNA. Its level in serum is decreased in patients with breast cancer. It can be incorporated into siRNA targeting the gene encoding apolipoprotein B, which decreases ApoB protein levels in HepG2 and prevents IFN-α production in isolated human PBMCs.
- Found in *T. thermophile* tRNA
- Decreased serum levels in breast cancer patients
- Can be incorporated into siRNA
- Decreases ApoB protein levels in HepG2
- Prevents IFN-α production in isolated human PBMCs
Sigma Aldrich Fine Chemicals Biosciences 2'-Deoxycytidine 5'-monophosphate Sigma Grade, >=95.0% | 1032-65-1 | MFCD00006546 | 1G
2'-Deoxycytidine 5'-monophosphate Sigma Grade, >=95.0% | Purity: >=95.0% | Mol Wt: 307.2 | 1032-65-1 | MFCD00006546 | 1G
Medchemexpress LLC Nucleoside-Analog-1 | 876707-99-2 | >95.0% | C9H9N5O5 | 50 MG
Nucleoside-Analog-1 is a click chemistry reagent containing an azide group. It can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups, and in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Click chemistry reagent containing an azide group.
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Biotium BrdU (5-Bromo-2'-Deoxyuridine)
BrdU (5-Bromo-2′-deoxyuridine) can be incorporated into DNA during cell division and subsequently detected by a BrdU antibody. The probe is useful for studying cell-cycle kinetics. Properties: White solid soluble in DMSO; Store at -20⁰C; C9H11BrN2O5; MW: 307.10; [59-14-3].
Medchemexpress LLC Pseudouridine | 1445-07-4 | MFCD00038458 | 99.9% | 244.20 | 5 MG
Pseudouridine is an isomer of uridine and the most abundant modified nucleoside in non-coding RNA. It fine-tunes and stabilizes regional structures in rRNA and tRNA, maintaining their functions in mRNA decoding, ribosome assembly, processing, and translation. Pseudouridine-modified tRNA fragments can inhibit aberrant protein synthesis and hold promise for research on myelodysplastic syndrome (MDS)-related leukemia.
- Most abundant modified nucleoside in non-coding RNA
- Fine-tunes and stabilizes regional structures in rRNA and tRNA
- Maintains functions in mRNA decoding, ribosome assembly, processing, and translation
- Inhibits aberrant protein synthesis
- Forms additional hydrogen bonds, stabilizing RNA and improving base stacking
- Found in all three phylogenetic domains of life
Medchemexpress LLC HY-16445 5mg Medchemexpress, Sapacitabine CAS:151823-14-2 Purity:>98%
Medchemexpress, HY-16445 5mg Sapacitabine CAS:151823-14-2 Sapacitabine is an orally available nucleoside analog prodrug that is structurally related to cytarabine. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.